KNOW YOUR GENOTYPE BEFORE MARRIAGE
A genotype is the entire genetic constitution of an individual, i.e. the genetic makeup of an organism or group of organisms with reference to a single trait, set of traits, or an entire complex of traits. In a nutshell: your genotype is your complete heritable genetic identity; the sum total of genes transmitted from parent to offspring.
There are four hemoglobin genotypes (hemoglobin pairs/formations) in humans: AA, AS, SS and AC (uncommon). SS and AC are the abnormal genotypes or the sickle cells. We all have a specific pair of these hemoglobin in our blood which we inherited from both parents
Knowing one’s hemoglobin genotype before choosing a life partner is important because there may be compatibility issues which could have devastating effects when it comes to conception.
Individuals with sickle cells experience severe pains in body parts where oxygen flow is compromised due to blockage in the blood vessels.
• AA can marry anybody
• AS is better off with AA
• AS and AS, AS and AC are too risky
• Two sickle cells = avoid conception
According to research, Nigeria has the largest population of people with sickle cell anaemia (or sickle cell disease aka SCD) in the world. Every year, more than 150 000 babies are born with this serious condition. Also alarming is the estimation that only 5% of the affected babies in Nigeria live passed the age of 10 (in UK and USA over 96% of sufferers survive into adulthood). Those with SCD often struggle with education, employment and psychological development due to chronic pain and other complications associated with the disease.
The main symptom is recurrent episodes of pain, called crises. The pain is caused by the sickle-shaped red blood cells blocking blood flow to the chest, abdomen and joints. The intensity of the pain varies, but it can last for hours or even weeks. Other symptoms include:
• Painful swelling of hands and feet
• Frequent infections
• Delayed growth
• Vision problems
Credit : https://www.thebridgeclinic.com
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